[1]陶雪瑩,岑 超,何俐瑩.鹽酸氨溴索聯合通竅鼻炎顆粒治療幼兒分泌性中耳炎的臨床效果[J].醫學信息,2019,(20):145-146,149.[doi:10.3969/j.issn.1006-1959.2019.20.045]
 TAO Xue-ying,CEN Chao,HE Li-ying.Clinical Effect of Ambroxol Hydrochloride Combined with Tongqiao Rhinitis Granules in the Treatment of Secretory Otitis Media in Children[J].Medical Information,2019,(20):145-146,149.[doi:10.3969/j.issn.1006-1959.2019.20.045]
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鹽酸氨溴索聯合通竅鼻炎顆粒治療幼兒分泌性中耳炎的臨床效果()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2019年20期
頁碼:
145-146,149
欄目:
藥物與臨床
出版日期:
2019-10-15

文章信息/Info

Title:
Clinical Effect of Ambroxol Hydrochloride Combined with Tongqiao Rhinitis Granules in the Treatment of Secretory Otitis Media in Children
文章編號:
1006-1959(2019)20-0145-03
作者:
陶雪瑩岑 超何俐瑩
(重慶市婦幼保健院眼耳鼻喉科,重慶 400010)
Author(s):
TAO Xue-yingCEN ChaoHE Li-ying
(Department of Otolaryngology,Chongqing Health Center for Women and Children,Chongqing 400010,China)
關鍵詞:
鹽酸氨溴索通竅鼻炎顆粒分泌性中耳炎
Keywords:
Ambroxol hydrochlorideTongqiao rhinitis granulesSecretory otitis media
分類號:
R764.21
DOI:
10.3969/j.issn.1006-1959.2019.20.045
文獻標志碼:
A
摘要:
目的 觀察鹽酸氨溴索聯合通竅鼻炎顆粒治療幼兒分泌性中耳炎的臨床效果。方法 選取2015年3月~2017年9月我院診治的分泌性中耳炎患者120例(170耳),按照隨機數字表法分為治療組60例(90耳)與對照組60例(80耳)。對照組口服鹽酸氨溴索,治療組在對照組基礎上加用通竅鼻炎顆粒,比較兩組治療前后咽鼓管功能正常占比、臨床療效及不良反應率。結果治療后,治療組咽鼓管功能正常占比為72.22%,高于對照組53.75%,差異具有統計學意義(P<0.05);治療組總有效率為81.11%,高于對照組的62.50%,差異具有統計學意義(P<0.05);治療組不良反應總發生率為8.33%,高于對照組的6.67%,但差異無統計學意義(P>0.05)。結論 鹽酸氨溴索聯合通竅鼻炎顆粒治療幼兒分泌性中耳炎,可促進咽鼓管功能恢復正常,臨床療效確切,且無明顯不良反應發生,安全有效。
Abstract:
Objective To observe the clinical effect of ambroxol hydrochloride combined with Tongqiao rhinitis granules in the treatment of secretory otitis media in children.Methods A total of 120 patients (170 ears) with secretory otitis media diagnosed in our hospital from March 2015 to September 2017 were enrolled. According to the random number table, 60 patients (90 ears) and 60 patients (80 ears) were included in the control group.The control group received oral ambroxol hydrochloride, and the treatment group added Tongqiao rhinitis granules on the basis of the control group. The normal proportion of eustachian tube function, clinical efficacy and adverse reaction rate were compared before and after treatment.Results After treatment, the normal proportion of eustachian tube function in the treatment group was 72.22%, which was higher than that in the control group 53.75%,the difference was statistically significant (P<0.05). The total effective rate of the treatment group was 81.11%, higher than that of 62.50% in control group,the difference was statistically significant (P<0.05). The total incidence of adverse reactions in the treatment group was 8.33%, which was higher than that of 6.67% in the control group, but the difference was not statistically significant (P>0.05).Conclusion Ambroxol hydrochloride combined with Tongqiao rhinitis granules in the treatment of secretory otitis media in children can promote the recovery of eustachian tube function, and the clinical curative effect is clear, and no obvious adverse reactions occur, which is safe and effective.

參考文獻/References:

[1]Wu HL,Xie YR.Pathogenesis and current status of treatment of secretory otitis media[J].Acta Medicinae Sinica,2014,27(2):l51-153. [2]李大鵬,黃輝,何苗,等.分泌性中耳炎的臨床診治進展[J].中國耳科學雜志,2017,15(1):98-101. [3]侯薇,張鐵英.鹽酸氨溴索聯合糖皮質激素治療分泌性中耳炎的療效觀察[J].中國生化藥物雜志,2017,37(7):191-193. [4]孔維佳.實用耳鼻咽喉頭頸外科學[M].北京:人民衛生出版社,2010:1165-1170. [5]李英來,逯素艷,高永海.歐龍馬滴劑治療6~12個月嬰兒分泌性中耳炎療效和安全性研究[J].河北醫藥,2017,39(8):1248-1253. [6]雷靜,吳小松.鹽酸氨溴索聯合桉檸蒎腸溶軟膠囊治療分泌性中耳炎的臨床效果分析[J].西部醫學,2016,9(28):1279-1282. [7]俞靜,王雁.通竅鼻炎顆粒治療鼻竇炎療效觀察[J].中國藥師,2014,17(2):264-265. [8]徐艷,馬梅,張宗強.通竅鼻炎顆粒聯合針刺治療過敏性鼻炎及對患者血清IL-4,IL-6及IL-10的影響[J].中國實驗方劑學雜志,2015,21(14):169-171.

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更新日期/Last Update: 2019-10-15
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