[1]顏俊文,顏小庚.腦梗死患者早期血清中Hs-CRP、HGMB1與梗死體積關系的研究[J].醫學信息,2019,(20):89-90.[doi:10.3969/j.issn.1006-1959.2019.20.024]
 YAN Jun-wen,YAN Xiao-geng.Relationship Between Serum Hs-CRP,HGMB1 and Infarct Volume in Patients with Cerebral Infarction[J].Medical Information,2019,(20):89-90.[doi:10.3969/j.issn.1006-1959.2019.20.024]
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腦梗死患者早期血清中Hs-CRP、HGMB1與梗死體積關系的研究()
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醫學信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期數:
2019年20期
頁碼:
89-90
欄目:
臨床研究
出版日期:
2019-10-15

文章信息/Info

Title:
Relationship Between Serum Hs-CRP,HGMB1 and Infarct Volume in Patients with Cerebral Infarction
文章編號:
1006-1959(2019)20-0089-02
作者:
顏俊文1顏小庚2
(遵義醫科大學第五附屬<珠海>醫院神經內科1,新生兒科2,廣東 珠海 519100)
Author(s):
YAN Jun-wen1YAN Xiao-geng2
(Department of Neurology1,Department of Neonatology2, Hospital,the Fifth Affiliated Hospital of Zunyi Medical University Zhuhai 519100,Guangdong,China)
關鍵詞:
腦梗死超敏C反應蛋白高遷移率族蛋白B1
Keywords:
Cerebral infarctionHypersensitive C-reactive proteinHigh mobility group protein B1
分類號:
R743.3
DOI:
10.3969/j.issn.1006-1959.2019.20.024
文獻標志碼:
A
摘要:
目的 探討急性腦梗死患者血清中超敏C反應蛋白(hs-CRP)、高遷移率族蛋白(HMGB1)水平變化與腦梗死體積的關系。方法 選取2017年1月~2019年1月我院收治的急性腦梗死患者40例,根據梗死體積分為急性腦梗死A組(體積<5 cm3)和急性腦梗死B組(體積>5 cm3),各20例,選取同期我院體檢健康者康20例設為對照組。比較各組入院后第2、4、7天血清中hs-CRP和HGMB1水平。結果 急性腦梗死組入院后第2、4、7天血清中hs-CRP和HGMB1水平均高于對照組,且B組高于A組,差異有統計學意義(P<0.05)。結論 急性腦梗死患者血清中hs-CRP和HGMB1水平均升高,且隨腦梗死體積增大而升高,監測其水平可判斷疾病預后。
Abstract:
Objective To investigate the relationship between serum levels of high-sensitivity C-reactive protein (Hs-CRP) and high-mobility group protein (HMGB1) and the volume of cerebral infarction in patients with acute cerebral infarction.Methods 40 patients with acute cerebral infarction admitted to our hospital from January 2017 to January 2019 were divided into acute cerebral infarction group A (volume <5 cm3) and acute cerebral infarction group B (volume>5 cm3).In each of the 20 cases, 20 cases of healthy people in our hospital were selected as the control group. Serum hs-CRP and HGMB1 levels were compared on days 2, 4, and 7 after admission.Result The levels of serum Hs-CRP and HGMB1 in acute cerebral infarction group were higher than those in control group on the 2nd, 4th and 7th day after admission, and the levels in group B were higher than those in group A, the difference was statistically significant (P<0.05).Conclusion The serum levels of Hs-CRP and HGMB1 in patients with acute cerebral infarction increase, and increase with the increase of cerebral infarction volume. Monitoring the level can judge the prognosis of the disease.

參考文獻/References:

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更新日期/Last Update: 2019-10-15
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